The top 25 papers in diabetes research are quite diverse; they include genetic and pathologic studies in both animals and humans as well as clinical trials. The genetic studies include phenotype analyses between genes associated with obesity and those associated with diabetes; comparative genetic maps of mouse and human genomes; and studies of genetic mutations present in particular diabetic pedigrees. Clinical studies making the top 25 include major trials examining the effects of particular medications, such as insulin therapy, thiazolidinediones, and angiotensin-converting enzyme inhibitors, on various aspects of diabetes; studies of different population segments; and studies examining pathogenic factors, such as oxidative stress and glycosylation, that result in diabetes or diabetic complications. Other factors of concern for diabetic patients, including obesity, cardiovascular risk, and mortality statistics compared with non-diabetic subjects, are also among the most-cited papers.
Methodology
To construct this database,
papers were extracted based on title- and author-supplied keywords for
the Special Topic: Diabetes. The keyword used was: diabetes.
The baseline time span for this database
is 1991 - October 2001. The resulting database contained 34,378 papers;
65,709
authors; 141 countries; 1,882 journals; and 10,205 institutions.
Rankings
Once the database was in place,
it was used to generate the lists of top 25 papers, authors, journals,
institutions, and nations, covering a time span of 1991 - October
2001.
The top 25 papers are ranked
according to total cites. Rankings for author, journal, institution,
and country are listed in three ways: according to total
cites, total papers, and total cites/paper.