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ESI Special Topics, April 2007
Citing URL: http://www.esi-topics.com/erf/maps/april2007-map.html
   

This Research Front on MEDICINAL ORGANOMETALLIC CHEMISTRY from the field of Chemistry was selected for mapping from the list of Emerging Research Fronts for April 2007 (data from the sixth bimonthly period of 2006). The map is a diagrammatic representation of the 10 core papers comprising the front. Each circle represents a highly cited paper whose bibliographic information is displayed when the user clicks on the circle. The lines between circles represent the strongest co-citation links for each paper (that is, indicating that the papers are frequently cited together). Papers close to each other on the map are generally more highly co-cited. The most recent paper(s) are indicated in red.


Emerging Research Fronts Comments
Peter J. Sadler & Yaw Kai Yan talk about thier highly cited paper, "Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes," (CHEM COMMUN, (38): 4764-4776, 2005) which is this month's emerging research front in Chemistry. This paper is represented in the map below.

Morris-2001 Chen-2002 Fish-2003 Allardyce-2005 Yan-2005 Wang-2005 Bregman-2006 Scolaro-2006 Schatzschneider-2006 Dyson-2006

 MEDICINAL ORGANOMETALLIC CHEMISTRY  


 Core Papers 


Label: Morris-2001
Title: Inhibition of cancer cell growth by ruthenium(II) arene complexes
Journal: J MED CHEM, 44 (22): 3616-3621 OCT 25 2001
Citations: 79
Authors: Morris, RE;Aird, RE;Murdoch, PD;Chen, HM;Cummings, J;Hughes, ND;Parsons, S;Parkin, A;Boyd, G;Jodrell, DI;Sadler, PJ
Addresses:
Univ Edinburgh, Dept Chem, W Mains Rd, Edinburgh EH9 3JJ, Midlothian, Scotland
Univ Edinburgh, Dept Chem, Edinburgh EH9 3JJ, Midlothian, Scotland
Western Gen Hosp, Med Oncol Unit, Imperial Canc Res Fund, Edinburgh EH4 2XU, Midlothian, Scotland


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Label: Chen-2002
Title: Organometallic ruthenium(II) diamine anticancer complexes: Arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts
Journal: J AM CHEM SOC, 124 (12): 3064-3082 MAR 27 2002
Citations: 75
Authors: Chen, HM;Parkinson, JA;Parsons, S;Coxall, RA;Gould, RO;Sadler, PJ
Addresses:
Univ Edinburgh, Dept Chem, W Mains Rd, Edinburgh EH9 3JJ, Midlothian, Scotland
Univ Edinburgh, Dept Chem, Edinburgh EH9 3JJ, Midlothian, Scotland


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Label: Fish-2003
Title: Bioorganometallic chemistry: Structural diversity of organometallic complexes with bioligands and molecular recognition studies of several supramolecular hosts with biomolecules, alkali-metal ions, and organometallic pharmaceuticals
Journal: ORGANOMETALLICS, 22 (11): 2166-2177 MAY 26 2003
Citations: 54
Authors: Fish, RH;Jaouen, G
Addresses:
Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Berkeley, CA 94720 USA
Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Berkeley, CA 94720 USA
Ecole Natl Super Chim Paris, UMR CNRS 7576, Lab Chim Organomet, F-75213 Paris 05, France


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Label: Allardyce-2005
Title: Development of organometallic (organo-transition metal) pharmaceuticals
Journal: APPL ORGANOMETAL CHEM, 19 (1): 1-10 JAN 2005
Citations: 20
Authors: Allardyce, CS;Dorcier, A;Scolaro, C;Dyson, PJ
Addresses:
Ecole Polytech Fed Lausanne, BCH, Inst Sci & Ingn Chim, CH-1015 Lausanne, Switzerland
Ecole Polytech Fed Lausanne, BCH, Inst Sci & Ingn Chim, CH-1015 Lausanne, Switzerland


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Label: Yan-2005
Title: Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes
Journal: CHEM COMMUN, (38): 4764-4776 2005
Citations: 20
Authors: Yan, YK;Melchart, M;Habtemariam, A;Sadler, PJ
Addresses:
Nanyang Technol Univ, Natl Inst Educ, 1 Nanyang Walk, Singapore 637616, Singapore
Univ Edinburgh, Sch Chem, Edinburgh EH9 3JJ, Midlothian, Scotland


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Label: Scolaro-2006
Title: Influence of hydrogen-bonding substituents on the cytotoxicity of RAPTA compounds
Journal: ORGANOMETALLICS, 25 (3): 756-765 JAN 30 2006
Citations: 9
Authors: Scolaro, C;Geldbach, TJ;Rochat, S;Dorcier, A;Gossens, C;Bergamo, A;Cocchietto, M;Tavernelli, I;Sava, G;Rothlisberger, U;Dyson, PJ
Addresses:
Callerio Fdn Onlus, Via A Fleming 22-31, I-34127 Trieste, Italy
Callerio Fdn Onlus, I-34127 Trieste, Italy
Ecole Polytech Fed Lausanne, Inst Sci & Ingn Chim, CH-1015 Lausanne, Switzerland
Univ Trieste, Dipartimento Sci Biomed, I-34127 Trieste, Italy


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Label: Bregman-2006
Title: Rapid access to unexplored chemical space by ligand scanning around a ruthenium center: Discovery of potent and selective protein kinase inhibitors
Journal: J AM CHEM SOC, 128 (3): 877-884 JAN 25 2006
Citations: 8
Authors: Bregman, H;Carroll, PJ;Meggers, E
Addresses:
Univ Penn, Dept Chem, 231 S 34th St, Philadelphia, PA 19104 USA
Univ Penn, Dept Chem, Philadelphia, PA 19104 USA


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Label: Wang-2005
Title: Controlling ligand substitution reactions of organometallic complexes: Tuning cancer cell cytotoxicity
Journal: PROC NAT ACAD SCI USA, 102 (51): 18269-18274 DEC 20 2005
Citations: 7
Authors: Wang, FY;Habtemariam, A;van der Geer, EPL;Fernandez, R;Melchart, M;Deeth, RJ;Aird, R;Guichard, S;Fabbiani, FPA;Lozano-Casal, P;Oswald, IDH;Jodrell, DI;Parsons, S;Sadler, PJ
Addresses:
Univ Edinburgh, Sch Chem, W Mains Rd, Edinburgh EH9 3JJ, Midlothian, Scotland
Univ Edinburgh, Sch Chem, Edinburgh EH9 3JJ, Midlothian, Scotland
Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England
Univ Edinburgh, Ctr Canc Res, CRUK Pharmacol & Drug Dev Team, Canc Res UK Oncol Unit, Edinburgh EH4 2XR, Midlothian, Scotland


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Label: Dyson-2006
Title: Metal-based antitumour drugs in the post genomic era
Journal: DALTON TRANS, (16): 1929-1933 2006
Citations: 6
Authors: Dyson, PJ;Sava, G
Addresses:
Ecole Polytech Fed Lausanne, Inst Sci & Ingn Chim, CH-1015 Lausanne, Switzerland
Ecole Polytech Fed Lausanne, Inst Sci & Ingn Chim, CH-1015 Lausanne, Switzerland
Callerio Fdn Onlus, I-34127 Trieste, Italy
Univ Trieste, Dipartimento Sci Biomed, I-34127 Trieste, Italy


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Label: Schatzschneider-2006
Title: New principles in medicinal organometallic chemistry
Journal: ANGEW CHEM INT ED, 45 (10): 1504-1507 2006
Citations: 6
Authors: Schatzschneider, U;Metzler-Nolte, N
Addresses:
Univ Heidelberg, Inst Pharm & Mol Biotechnol, Im Neuenheimer Feld 364, D-69120 Heidelberg, Germany
Univ Heidelberg, Inst Pharm & Mol Biotechnol, D-69120 Heidelberg, Germany
Ruhr Univ Bochum, D-44801 Bochum, Germany


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ESI Special Topics, April 2007
Citing URL: http://www.esi-topics.com/erf/maps/april2007-map.html

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