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ESI Special Topics,
February 2007 Citing URL: http://www.esi-topics.com/erf/maps/february2007-map.html
This Research Front on
KIT MUTATIONS AND CANCER from the field of Clinical
Medicine was selected for mapping from the list of Emerging Research Fronts
for February 2007 (data from
the fifth bimonthly period
of 2006). The map is a diagrammatic
representation of the 30 core papers comprising the front. Each
circle represents a highly cited paper whose bibliographic
information is displayed when the user clicks on the circle. The
lines between circles represent the strongest co-citation links
for each paper (that is, indicating that the papers are frequently
cited
together). Papers close to each other on the map are generally
more highly co-cited. The most recent paper(s)
are indicated in red.
Core Papers
Label: Cools-2003 Title: A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome Journal: N ENGL J MED, 348 (13): 1201-1214 MAR 27 2003 Citations: 335 Authors: Cools, J;DeAngelo, DJ;Gotlib, J;Stover, EH;Legare, RD;Cortes, J;Kutok, J;Clark, J;Galinsky, I;Griffin, JD;Cross, NCP;Tefferi, A;Malone, J;Alam, R;Schrier, SL;Schmid, J;Rose, M;Vandenberghe, P;Verhoef, G;Boogaerts, M;Wlodarska, I;Kantarjian, H;Marynen, P;Coutre, SE;Stone, R;Gilliland, DG Addresses:
Harvard Univ, Inst Med, 4 Blackfan Cir,Rm 418, Boston, MA 02115 USA
Harvard Univ, Brigham & Womens Hosp, Sch Med, Boston, MA 02115 USA
Dana Farber Canc Inst, Boston, MA 02115 USA
Stanford Univ, Med Ctr, Sch Med, Stanford, CA 94305 USA
Brown Univ, Women & Infants Hosp, Sch Med, Providence, RI USA
Westerly Hosp, Westerly, RI USA
Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA
Wessex Reg Genet Lab, Salisbury, Wilts, England
Mayo Clin, Rochester, MN USA
Natl Jewish Med & Res Ctr, Denver, CO USA
Tulane Univ, Sch Med, New Orleans, LA 70112 USA
Yale Univ, Sch Med, New Haven, CT USA
Univ Hosp Leuven, Louvain, Belgium
Flanders Interuniv Inst Biotechnol, Louvain, Belgium
Catholic Univ Louvain, Ctr Human Genet, B-3000 Louvain, Belgium
Brigham & Womens Hosp, Howard Hughes Med Inst, Boston, MA 02115 USA
Label: Apperley-2002 Title: Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta Journal: N ENGL J MED, 347 (7): 481-487 AUG 15 2002 Citations: 214 Authors: Apperley, JF;Gardembas, M;Melo, JV;Russell-Jones, R;Bain, BJ;Baxter, J;Chase, A;Chessells, JM;Colombat, M;Dearden, CE;Dimitrijevic, S;Mahon, FX;Marin, D;Nikolova, Z;Olavarria, E;Silberman, S;Schultheis, B;Cross, NCP;Goldman, JM Addresses:
Univ London Imperial Coll Sci Technol & Med, Dept Haematol, Fac Med, Hammersmith Hosp, Du Cane Rd, London W12 0NN, England
Ctr Hosp Univ Angers, Dept Hematol, Angers, France
St Thomas Hosp, Skin Tumour Unit, St Johns Inst Dermatol, London, England
Salisbury Dist Hosp, Wessex Reg Genet Lab, Salisbury, Wilts, England
Great Ormond St Hosp Children, Dept Haematol, London WC1N 3JH, England
Ctr Hosp Univ Bordeaux, Dept Hematol, Pessac, France
Univ London St Georges Hosp, Dept Haematol, London SW17 0RE, England
Novartis Oncol, Basel, Switzerland
Univ London Imperial Coll Sci Technol & Med, Dept Haematol, Fac Med, London, England
Label: Valent-2001 Title: Diagnostic criteria and classification of mastocytosis: a consensus proposal Journal: LEUK RES, 25 (7): 603-625 Sp. Iss. SI JUL 2001 Citations: 171 Authors: Valent, P;Horny, HP;Escribano, L;Longley, BJ;Li, CY;Schwartz, LB;Marone, G;Nunez, R;Akin, C;Sotlar, K;Sperr, WR;Wolff, K;Brunning, RD;Parwaresch, RM;Austen, KF;Lennert, K;Metcalfe, DD;Vardiman, JW;Bennett, JM Addresses:
Univ Vienna, Div Hematol, Dept Internal Med 1, Waehringer Guertel 18-20, A-1090 Vienna, Austria
Univ Vienna, Div Hematol, Dept Internal Med 1, A-1090 Vienna, Austria
Med Univ Lubeck, Inst Pathol, D-23538 Lubeck, Germany
Hosp Ramon y Cajal, Unidad Mastocitosis, Serv Hematol, E-28034 Madrid, Spain
Columbia Univ, Dept Dermatol, New York, NY 10027 USA
Columbia Univ, Dept Pathol, New York, NY 10027 USA
Mayo Clin & Mayo Fdn, Div Hematopathol, Rochester, MN 55905 USA
Virginia Commonwealth Univ, Med Coll Virginia, Dept Internal Med, Div Rheumatol Allergy & Immunol, Richmond, VA 23298 USA
Univ Naples Federico II, Cattedra Immunol Clin & Allergol, Fac Med & Chirurg, Naples, Italy
NIAID, Lab Allerg Dis, NIH, Bethesda, MD 20892 USA
Univ Tubingen, Inst Pathol, D-7400 Tubingen, Germany
Univ Vienna, Dept Dermatol, A-1090 Vienna, Austria
Univ Minnesota, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA
Univ Kiel, Inst Hematopathol & Lymph Node Registry, Kiel, Germany
Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Rheumatol Allergy & Immunol, Boston, MA 02115 USA
Univ Chicago, Dept Pathol, Hematopathol Sect, Chicago, IL 60637 USA
Univ Rochester, Med Ctr, Ctr Canc, Med Oncol Unit, Rochester, NY 14642 USA
Label: Ma-2002 Title: The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations Journal: BLOOD, 99 (5): 1741-1744 MAR 1 2002 Citations: 151 Authors: Ma, YS;Zeng, S;Metcalfe, DD;Akin, C;Dimitrijevic, S;Butterfield, JH;McMahon, G;Longley, BJ Addresses:
Columbia Univ, Coll Phys & Surg, Sect Dermatopathol, Dept Dermatol, 630 W 168th St, New York, NY 10032 USA
Columbia Univ, Coll Phys & Surg, Sect Dermatopathol, Dept Dermatol, New York, NY 10032 USA
Columbia Univ, Coll Phys & Surg, Dept Pathol, New York, NY 10032 USA
NIAID, Lab Allerg Dis, NIH, Bethesda, MD 20892 USA
Novartis, Basel, Switzerland
Mayo Clin & Mayo Fdn, Dept Allerg Dis, Rochester, MN 55905 USA
SUGEN, San Francisco, CA USA
Label: Gleich-2002 Title: Treatment of hypereosinophilic syndrome with imatinib mesilate Journal: LANCET, 359 (9317): 1577-1578 MAY 4 2002 Citations: 122 Authors: Gleich, GJ;Leiferman, KM;Pardanani, A;Tefferi, A;Butterfield, JH Addresses:
4B454 Sch Med, Dept Dermatol, 30 North 1900 East, Salt Lake City, UT 84132 USA
4B454 Sch Med, Dept Dermatol, Salt Lake City, UT 84132 USA
Mayo Clin & Mayo Fdn, Dept Immunol, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Med, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Dermatol, Allerg Dis Res Lab, Rochester, MN 55905 USA
Label: Longley-2001 Title: Classes of c-KIT activating mutations: proposed mechanisms of action and implications for disease classification and therapy Journal: LEUK RES, 25 (7): 571-576 Sp. Iss. SI JUL 2001 Citations: 118 Authors: Longley, BJ;Reguera, MJ;Ma, YS Addresses:
Columbia Univ, Dept Dermatol, 630 W 168th St,VC-15-202, New York, NY 10031 USA
Columbia Univ, Dept Dermatol, New York, NY 10031 USA
Columbia Univ, Dept Pathol, New York, NY 10031 USA
Univ Autonoma Barcelona, Fac Vet, Dept Histol & Pathol, E-08193 Barcelona, Spain
Label: Rubin-2002 Title: Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans Journal: J CLIN ONCOL, 20 (17): 3586-3591 SEP 1 2002 Citations: 100 Authors: Rubin, BP;Schuetze, SM;Eary, JF;Norwood, TH;Mirza, S;Conrad, EU;Bruckner, JD Addresses:
Univ Washington, Med Ctr, Dept Anat Pathol, Box 356100,1959 NE Pacific St, Seattle, WA 98195 USA
Univ Washington, Med Ctr, Dept Pathol, Seattle, WA 98195 USA
Univ Washington, Med Ctr, Dept Med, Seattle, WA 98195 USA
Univ Washington, Med Ctr, Dept Nucl Med, Seattle, WA 98195 USA
Univ Washington, Med Ctr, Dept Orthoped, Seattle, WA 98195 USA
Label: Wang-2005 Title: AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: Implication in stepwise leukemogenesis and response to Gleevec Journal: PROC NAT ACAD SCI USA, 102 (4): 1104-1109 JAN 25 2005 Citations: 32 Authors: Wang, YY;Zhou, GB;Yin, T;Chen, B;Shi, JY;Liang, WX;Jin, XL;You, JH;Yang, G;Shen, ZX;Chen, J;Xiong, SM;Chen, GQ;Xu, F;Liu, YW;Chen, Z;Chen, SJ Addresses:
Shanghai Med Univ 2, Rui Jin Hosp, State Key Lab Med Genomics, 197 Rui Jin Rd 2, Shanghai 200025, Peoples R China
Shanghai Med Univ 2, Rui Jin Hosp, State Key Lab Med Genomics, Shanghai 200025, Peoples R China
Shanghai Med Univ 2, Rui Jin Hosp, Shanghai Inst Hematol, Shanghai 200025, Peoples R China
Shanghai Med Univ 2, Rui Jin Hosp, Dept Med Lab Sci, Ruijin Med Coll, Shanghai 200025, Peoples R China
Shanghai Med Univ 2, Rui Jin Hosp, Dept Pathol, Shanghai 200025, Peoples R China
Chinese Acad Sci, Shanghai Inst Biol Sci, Hlth Sci Ctr, Shanghai 200025, Peoples R China
Tsing Hua Univ, Inst Biol Sci, Beijing 100084, Peoples R China
Label: Valent-2005 Title: Mastocytosis: Pathology, genetics, and current options for therapy Journal: LEUK LYMPHOMA, 46 (1): 35-48 JAN 2005 Citations: 22 Authors: Valent, P;Akin, C;Sperr, WR;Mayerhofer, M;Fodinger, M;Fritsche-Polanz, R;Sotlar, K;Escribano, L;Arock, M;Horny, HP;Metcalfe, DD Addresses:
Med Univ Vienna, Dept Internal Med 1, Div Hematol & Hemostaseol, Wahringer Gurtel 18-20, Vienna, Austria
Med Univ Vienna, Dept Internal Med 1, Div Hematol & Hemostaseol, Vienna, Austria
Univ Michigan, Div Allergy, Ann Arbor, MI 48109 USA
Med Univ Vienna, Clin Inst Med & Chem Lab Diagnost, Vienna, Austria
Univ Tubingen, Inst Pathol, D-72074 Tubingen, Germany
Hosp Ramon y Cajal, Mast Cell Unit, E-28034 Madrid, Spain
Fac Pharm, CNRS, Unit UMR 8147, Paris, France
Univ Lubeck, Inst Pathol, Lubeck, Germany
NIAID, Lab Allerg Dis, NIH, Bethesda, MD 20892 USA
Label: Growney-2005 Title: Activation mutations of human c-KIT resistant to imatinib, mesylate are sensitive to the tyrosine kinase inhibitor PKC412 Journal: BLOOD, 106 (2): 721-724 JUL 15 2005 Citations: 21 Authors: Growney, JD;Clark, JJ;Adelsperger, J;Stone, R;Fabbro, D;Griffin, JD;Gilliland, DG Addresses:
Karp Family Res Bldg,1 Blackfan Circle,5th Fl, Boston, MA 02115 USA
Brigham & Womens Hosp, Dept Med, Div Hematol, Boston, MA 02115 USA
Dana Farber Canc Inst, Boston, MA 02115 USA
Novartis Pharma AG, Basel, Switzerland
Harvard Univ, Sch Med, Howard Hughes Med Inst, Boston, MA 02115 USA
Label: Schittenhelm-2006 Title: Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT Isoforms associated with human malignancies Journal: CANCER RES, 66 (1): 473-481 JAN 1 2006 Citations: 10 Authors: Schittenhelm, MM;Shiraga, S;Schroeder, A;Corbin, AS;Griffith, D;Lee, FY;Bokemeyer, C;Deininger, MWN;Druker, BJ;Heinrich, MC Addresses:
Portland Vet Affairs Med Ctr, R&D-19,3710 SW US Vet Hosp Rd, Portland, OR 97239 USA
Portland Vet Affairs Med Ctr, Portland, OR 97239 USA
Oregon Hlth Sci Univ, Dept Med, Div Hematol Oncol, Portland, OR 97201 USA
Bristol Myers Squibb Co, Oncol Drug Discovery, Princeton, NJ USA
Univ Hamburg, Med Ctr Eppendorf, Dept Med, Hamburg, Germany
Howard Hughes Med Inst, Chevy Chase, MD USA
Label: Adrian-2006 Title: Allosteric inhibitors of Bcr-abl-dependent cell proliferation Journal: NAT CHEM BIOL, 2 (2): 95-102 FEB 2006 Citations: 6 Authors: Adrian, FJ;Ding, Q;Sim, TB;Velentza, A;Sloan, C;Liu, Y;Zhang, GB;Hur, W;Ding, S;Manley, P;Mestan, J;Fabbro, D;Gray, NS Addresses:
Novartis Res Fdn, Dept Biol Chem, Genom Inst, 10675 John Jay Hopkins Dr, San Diego, CA 92121 USA
Novartis Res Fdn, Dept Biol Chem, Genom Inst, San Diego, CA 92121 USA
Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA
Novartis Inst Biomed Res, Oncol Res, CH-4002 Basel, Switzerland
Label: Parfitt-2006 Title: Eosinophilic esophagitis in adults: distinguishing features from gastroesophageal reflux disease: a study of 41 patients Journal: MODERN PATHOL, 19 (1): 90-96 JAN 2006 Citations: 6 Authors: Parfitt, JR;Gregor, JC;Suskin, NG;Jawa, HA;Driman, DK Addresses:
London Hlth Sci Ctr, Dept Pathol, 339 Windermere Rd, London, ON N6A 5A5, Canada
London Hlth Sci Ctr, Dept Pathol, London, ON N6A 5A5, Canada
Univ Western Ontario, London, ON, Canada
London Hlth Sci Ctr, Dept Med, London, ON N6A 5A5, Canada
Label: Shimada-2006 Title: KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): a study of the Japanese Childhood AML Cooperative Study Group Journal: BLOOD, 107 (5): 1806-1809 MAR 1 2006 Citations: 6 Authors: Shimada, A;Taki, T;Tabuchi, K;Tawa, A;Horibe, K;Tsuchida, M;Hanada, R;Tsukimoto, I;Hayashi, Y Addresses:
Gunma Childrens Med Ctr, Dept Hematol Oncol, 779 SHimohakoda, Kitatachibana, Gunma 3778577, Japan
Gunma Childrens Med Ctr, Dept Hematol Oncol, Kitatachibana, Gunma 3778577, Japan
Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Mol Lab Med, Kyoto 602, Japan
Kanagawa Childrens Med Ctr, Dept Hematol, Yokohama, Kanagawa, Japan
Natl Hosp Org, Osaka Natl Hosp, Dept Pediat, Osaka, Japan
Natl Hosp Org, Nagoya Med Ctr, Clin Res Ctr, Nagoya, Aichi, Japan
Ibaraki Childrens Hosp, Dept Pediat, Ibaraki, Japan
Toho Univ, Sch Med, Dept Pediat 1, Tokyo, Japan
Label: Shah-2006 Title: Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in most patients with systemic mastocytosis Journal: BLOOD, 108 (1): 286-291 JUL 1 2006 Citations: 5 Authors: Shah, NP;Lee, FY;Luo, R;Jiang, YB;Donker, M;Akin, C Addresses:
Univ Michigan, Div Allergy & Immunol, Sch Med, 4220-D MSRB-3,Box 0638,1150 W Med Ctr Dr, Ann Arbor, MI 48109 USA
Univ Michigan, Div Allergy & Immunol, Sch Med, Ann Arbor, MI 48109 USA
Univ Calif Los Angeles, David Geffen Sch Med, Div Hematol Oncol, Los Angeles, CA 90024 USA
Bristol Myers Squibb Oncol, Princeton, NJ USA
Univ Groningen, Med Ctr, NL-9700 AB Groningen, Netherlands
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