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This Research Front on CYTOCHROME P450 POLYMORPHISMS AND BLEEDING
from the field of Pharmacology & Toxicology
was selected for mapping from the list of Emerging Research Fronts
for October 2004 (data from
the third bimonthly period of 2004). The map is a diagrammatic
representation of the seven core papers comprising the front. Each
circle represents a highly cited paper whose bibliographic
information is displayed when the user clicks on the circle. The
lines between circles represent the strongest co-citation links
for each paper (that is, indicating that the papers are frequently cited
together). Papers close to each other on the map are generally
more highly co-cited.
Ann K. Daly
discusses her highly cited paper, "Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications,"
(LANCET, 353: (9154) 717-719, FEB 27 1999) which is this
month's emerging research front in pharmacology &
toxicology. This paper is also represented in the map
below.
Core Papers
Label: Aithal-1999 Title: Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications Journal: LANCET, 353: (9154) 717-719 FEB 27 1999 Citations: 219 Authors: Aithal, GP;Day, CP;Kesteven,
PJL;Daly, AK Addresses: Univ Newcastle Upon Tyne, Sch Med, Dept Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Univ Newcastle Upon Tyne, Sch Med, Dept Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Univ Newcastle Upon Tyne, Sch Med, Dept Pharmacol Sci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England by Ann K.
Daly - [late entry]
Label: Higashi-2002 Title: Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy Journal: JAMA-J AM MED ASSN, 287: (13) 1690-1698 APR 3 2002 Citations: 65 Authors: Higashi, MK;Veenstra, DL;Kondo, LML;Wittkowsky, AK;Srinouanprachanh, SL;Farin, FM;Rettie, AE Addresses:
Univ Washington, Dept Pharm, Box 357630, Hlth Sci Bldg, Room H-375A, Seattle, WA 98195 USA
Univ Washington, Med Ctr, Pharmaceut Outcomes Res & Policy Program, Seattle, WA 98195 USA
Univ Washington, Med Ctr, Inst Publ Hlth Genet, Seattle, WA 98195 USA
Univ Washington, Med Ctr, Dept Pharm Serv, Seattle, WA 98195 USA
Univ Washington, Ctr Ecogenet & Environm Hlth, Mol Biomarkers Lab, Seattle, WA 98195 USA
Univ Washington, Dept Med Chem, Seattle, WA 98195 USA
Label: Lee-2002 Title: Cytochrome P4502C9 polymorphisms: a comprehensive review of the in-vitro and human data Journal: PHARMACOGENETICS, 12: (3) 251-263 APR 2002 Citations: 45 Authors: Lee, CR;Goldstein, JA;Pieper, JA Addresses:
Univ N Carolina, Div Pharmacotherapy, CB7360, Beard Hall, Chapel Hill, NC 27599 USA
Univ N Carolina, Div Pharmacotherapy, Chapel Hill, NC 27599 USA
NIEHS, Res Triangle Pk, NC 27709 USA
Label: Kidd-2001 Title: Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin Journal: PHARMACOGENETICS, 11: (9) 803-808 DEC 2001 Citations: 33 Authors: Kidd, RS;Curry, TB;Gallagher, S;Edeki, T;Blaisdell, J;Goldstein, JA Addresses:
Shenandoah Univ, Bernard J Dunn Sch Pharm, Dept Biopharmaceut Sci, 1775 N Sector Court, Winchester, VA 22601 USA
Shenandoah Univ, Bernard J Dunn Sch Pharm, Dept Biopharmaceut Sci, Winchester, VA 22601 USA
SUNY Buffalo, Sch Med & Biomed Sci, Buffalo, NY 14260 USA
NIEHS, Res Triangle Pk, NC 27709 USA
Morehouse Sch Med, Atlanta, GA 30310 USA
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