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Fast Breaking Comments

By Andrey Rzhetsky

ESI Special Topics, August 2005
Citing URL - http://www.esi-topics.com/fbp/2005/august05-AndreyRzhetsky.html

Andrey Rzhetsky answers a few questions about this month's fast breaking paper in the field of Computer Science.

From •>>August 2005  - [late entry]

Field: Computer Science
Article Title: GeneWays: a system for extracting, analyzing, visualizing, and integrating molecular pathway data
 Authors: Rzhetsky, A;Iossifov, I;Koike, T;Krauthammer, M;Kra, P;Morris, M;Yu, H;Duboue, PA;Weng, WB;Wilbur, WJ;Hatzivassiloglou, V;Friedman, C
Journal: J BIOMED INFORM
Volume: 37
Page: 43-53
Year: FEB 2004
* Columbia Univ, Columbia Genome Ctr, New York, NY 10032 USA.
* Columbia Univ, Columbia Genome Ctr, New York, NY 10032 USA.
* Columbia Univ, Dept Biomed Informat, New York, NY 10032 USA.
* Columbia Univ, Ctr Computat Biol & Bioinformat, New York, NY 10032 USA.
* Columbia Univ, Dept Comp Sci, New York, NY 10032 USA.
* Hitachi Software Engn Co Ltd, Yokohama, Kanagawa, Japan.
* NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20984 USA.

ST:  Why do you think your paper is highly cited?


Click to see group photo.

It is a mystery! Seriously, our paper was cited about 10 times during the past year; that is not a remarkably frequent rate for a biological paper.

ST:  Does it describe a new discovery or new methodology that’s useful to others?

It describes GeneWays, a new kind of computer-based automatic tool that integrates several tasks of artificial intelligence in a single framework. GeneWays has immediate relevance to the field of molecular biology; with it, scientists can perform analyses in minutes that hitherto would have required a lifetime of work, and would have been outdated before completion.

ST:  Could you summarize the significance of your paper in layman’s terms?

The system finds, analyzes, and extracts relevant information from hundreds of thousands —potentially millions—of relevant research articles, then organizes this huge volume of data in a logical and accessible structure.

ST:  How did you become involved in this research?

We were conducting a large-scale study of a blood cancer, for which we had to overcome the practical difficulty of compiling an enormous body of published information.End

Andrey Rzhetsky, Ph.D.
Associate Professor
Department of Biomedical Informatics
Center for Computational Biology and Bioinformatics (C2B2)
and 
Columbia Genome Center
Columbia University
New York, NY, USA

ESI Special Topics, August 2005
Citing URL - http://www.esi-topics.com/fbp/2005/august05-AndreyRzhetsky.html

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