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Fast Breaking Comments

By Kristina Melkersson

ESI Special Topics, August 2005
Citing URL - http://www.esi-topics.com/fbp/2005/august05-KristinaMelkersson.html

Kristina Melkersson answers a few questions about this month's fast breaking paper in the field of Pharmacology & Toxicology.


From •>>August 2005  - [late entry]

Field: Pharmacology & Toxicology
Article Title: Adverse metabolic effects associated with atypical antipsychotics - Literature review and clinical implications
Authors: Melkersson, K;Dahl, ML
Journal: DRUGS
Volume: 64
Page: 701-723
Year: 2004
* Sollentuna Hosp, Psychiat Polyclin, Nytorpsvagen 10-12, SE-19135 Sollentuna, Sweden.
* Karolinska Inst, Sollentuna Psychiat Polyclin, Stockholm, Sweden.
* Karolinska Inst, Dept Mol Med, Stockholm, Sweden.
* Univ Uppsala Hosp, Dept Med Sci, Uppsala, Sweden.

ST:  Why do you think your paper is highly cited?


“...(the paper) provides clinical recommendations for prevention and treatment of the adverse metabolic effects of atypical antipsychotics.”

It focuses on a clinically important issue—the adverse metabolic effects of the newer, so-called atypical antipsychotic drugs.

ST:  Does it describe a new discovery or a new methodology that’s useful to others?

The paper, which was co-written by Professor Marja-Liisa Dahl and me, is a review of the current literature in the field. It also provides clinical recommendations for prevention and treatment of the adverse metabolic effects of atypical antipsychotics.

ST:  Could you summarize the significance of your paper in layman’s terms?

Adverse metabolic effects of atypical antipsychotics may have a negative influence on both the antipsychotic treatment outcome as well as the physical health of the patient. Therefore, these effects have to be recognized and adequately managed. In this respect, this paper is important and well worth reading.

ST:  How did you become involved in this research?

I became involved in psychoendocrinological research when I was an assistant physician at the Department of Endocrinology, Karolinska Hospital, Stockholm, 15 years ago. Later on, in the year 2000, I gained my doctor’s degree with a dissertation titled: "Influence of antipsychotic drugs on hormone levels." Since then, I have continued researching within this field.End

Kristina Melkersson, M.D.
Department of Molecular Medicine
Karolinska Institute
Stockholm, Sweden

ESI Special Topics, August 2005
Citing URL - http://www.esi-topics.com/fbp/2005/august05-KristinaMelkersson.html

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