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Fast Breaking Comments

By Steven P. Nolan

ESI Special Topics, August 2007
Citing URL - http://www.esi-topics.com/fbp/2007/august07-StevenPNolan.html

Steven P. Nolan answers a few questions about this month's fast breaking paper in the field of Chemistry.


From •>>August 2007

Field: Chemistry
Article Title: Au-I-catalyzed tandem [3,3] rearrangement-intramolecular hydroarylation: Mild and efficient formation of substituted indenes
Authors: Marion, N;Diez-Gonzalez, S;de Fremont, P;Noble, AR;Nolan, SP
Journal: ANGEW CHEM INT ED
Volume: 45
Issue: 22
Page: 3647-3650
Year: 2006
* Univ New Orleans, Dept Chem, 2000 Lakeshore Dr, New Orleans, LA 70148 USA.
* Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA.

ST:  Why do you think your paper is highly cited?Dr. Nolan's Group

Gold catalysis is a very rapidly developing area and our indene synthesis methodology is quite straightforward and very versatile.

ST:  Does it describe a new discovery, methodology, or synthesis of knowledge?

It’s a methodology which is easy to use with a gold precatalyst that can now be obtained from Strem Chemicals, Inc.

ST:  Would you summarize the significance of your paper in layman’s terms?

It permits easy assembly of complex structure in one step in air.

ST:  How did you become involved in this research, and were there any problems along the way?

I have been involved in NHC (N-heterocyclic carbene) transition metal catalysis for almost 10 years now. Gold seemed like an area worth investigating. Problems...yes, there are always problems, but we solved them fairly straightforwardly.

ST:  Where do you see your research leading in the future?

These Gold-NHC complexes are very stable and will open areas where gold-phosphine complexes fail.

ST:  Are there any social or political implications for your research?

None, our indene synthesis methodology just helps make molecules easily, in a catalytic way with limited waste.End

Professor Steven P. Nolan
Institute of Chemical Research of Catalonia (ICIQ)
Tarragona, Spain

Read another comment (Emerging Research Front) from Steven Nolan.

ESI Special Topics, August 2007
Citing URL - http://www.esi-topics.com/fbp/2007/august07-StevenPNolan.html

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