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Fast Breaking Comments

By Dr Philippe Seguela

ESI Special Topics, February 2002
Citing URL - http://www.esi-topics.com/fbp/comments/february02-PhilippeSeguela.html

Dr Philippe Seguela answers a few questions about this month's fast breaking paper in field of Pharmacology & Toxicology.

From •>>February 2002

Field: Pharmacology & Toxicology
Article Title: "International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits"
 Authors: Khakh, BS;Burnstock, G;Kennedy, C;King, BF;North, RA, Seguela, P; P;Voigt, M;Humphrey, PPA
Journal: PHARMACOL REV
Volume: 53
Page: 107-118
Year: MAR 2001
* MRC, Mol Biol Lab, Div Neurobiol, Hills Rd, Cambridge CB2 2QH, England.
* CALTECH, Div Biol 156 29, Pasadena, CA 91125 USA.
* Royal Free Hosp, Sch Med, Auton Neurosci Inst, London, England.
* Univ Strathclyde, Dept Physiol & Pharmacol, Royal Coll, Glasgow G1 1XW, Lanark, Scotland.
* Univ Sheffield, Western Bank, Inst Mol Physiol, Sheffield, S Yorkshire, England.
* McGill Univ, Montreal Neurol Inst, Dept Neurol & Neurosurg, Montreal, PQ H3A 2B4, Canada.
* St Louis Univ, Sch Med, St Louis, MO USA.
* Univ Cambridge, Dept Pharmacol, Glaxo Inst Appl Pharmacol, Cambridge CB2 1QJ, England.

ST:  Why do you think your paper is highly cited? 

It presents an up-to-date picture of the pharmacology and biology of P2X ATP receptors.

ST:  Is it a condensation of previous literature on the subject?

Yes, it summarizes the expanding literature available on P2X ATP receptors.

ST:  Could you summarize the significance of your paper in layman's terms?

ATP is a neurotransmitter and also a pain messenger, so the properties of ATP receptors are both biologically and clinically relevant.End

Dr. Philippe Seguela
Associate Professor
Montreal Neurological Institute
McGill University
3801 University
Montreal (Quebec) Canada H3A 2B4

ESI Special Topics, February 2002
Citing URL - http://www.esi-topics.com/fbp/comments/february02-PhilippeSeguela.html

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