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From
•>>July 2004
Carson Meredith answers
a few questions about this month's fast moving front in the
field of Chemistry.
Field: Chemistry
Article: Combinatorial methods for investigations in polymer materials science
Authors: Meredith,
JC;Karim, A;Amis, EJ
Journal: MRS BULL, 27: (4) 330-335, APR 2002
Addresses:
Georgia Inst Technol, Sch Chem Engn, Atlanta, GA 30332 USA.
Georgia Inst Technol, Sch Chem Engn, Atlanta, GA 30332 USA.
Natl Inst Stand & Technol, Div Polymer, Multivariant Measurement Methods Grp, Gaithersburg, MD USA.
Natl Inst Stand & Technol, Combinatorial Methods Ctr, Gaithersburg, MD
USA.
for Chemistry.
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Why
do you think your paper is highly cited?
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“...this work profiles the very first successful demonstrations of a new technique for performing research and developing new materials.”
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The combinatorial materials science field is less than a
decade old, and really only began to gain momentum within the
past several years. This is particularly true for polymeric
materials, of which most of our everyday and high-technology
products are composed, at least in part. In 2002, there were
few, if any, comprehensive reviews of the polymer combinatorial
methods research field. The coauthors, Eric Amis and Alamgir
Karim, and I are among the first handful of researchers to
demonstrate successful combinatorial polymer science.
Does
it describe a new discovery or new methodology that's useful to
others?
Absolutely. The combinatorial method, applied in an
appropriate manner, can reduce by an order of magnitude or more
the time and cost of developing a new material. This is of
interest to a broad range of chemical companies that manufacture
plastics, as well as to scientists who need to have an efficient
method for "mapping" the response of a certain
material to large numbers of variables.
Could
you summarize the significance of your paper in layman's terms?
In layman’s terms, this work profiles the very first
successful demonstrations of a new technique for performing
research and developing new materials. The applications are
boundless and include medical devices, engineered tissues, fuel
cells, and other environmental materials, and new ways to
process and package electronics. The methods, called
"combinatorial methods" allow about 1,000 tests to be
performed in the time that it used to take for one test. The
ability to quickly identify materials that do, or do not, work
for an application is ever more important for industries where
the time to get the product to market often governs who will be
the industry leader.
How
did you become involved in this research?
Although I am now a professor of Chemical and Biomolecular
Engineering at Georgia Tech, the work really began during my
post doc at the National Institute of Standards and Technology (NIST),
under the direction of Eric Amis. The idea for combinatorial
polymer science came out of discussions centering on the
extremely large number of parameters one can vary in polymers
and the relative inability of conventional "detailed"
techniques to handle this breadth. At the time that we began,
there were no standardized or accepted methods or instruments
commercially available to make polymer combinatorial libraries.
So we had to start from scratch and develop novel techniques
ourselves. This effort has continued to grow stronger since I
have moved to Georgia Tech.
Carson Meredith
Assistant Professor
School of Chemical & Biomolecular Engineering
Georgia Tech
Atlanta, Georgia, USA
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