By Mitsuru Yoshida
ESI Special Topics,
July 2004
Citing URL - http://www.esi-topics.com/nhp/2004/july-04-MitsuruYoshida.html
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Mitsuru Yoshida answers a few questions about this month's
new hot paper in the field of Agricultural Sciences.
From
•>>July 2004
Field:
Agricultural Sciences
Article Title: Analysis of acrylamide by LC-MS/MS and GC-MS in processed Japanese foods
Authors: Ono, H;Chuda, Y;Ohnishi-Kameyama, M;Yada, H;Ishizaka, M;Kobayashi,
H;Yoshida, M
Journal: FOOD ADDIT CONTAM
Volume: 20
Page: 215-220
Year: 2003
* Natl Food Res Inst, 2-1-2 Kannondai, Tsukuba, Ibaraki 3058642, Japan.
* Natl Food Res Inst, Tsukuba, Ibaraki 3058642, Japan.
* Ctr Food Qual Labeling & Consumer Serv, Kitabukuro, Saitama 3309731, Japan.
* Natl Inst Agroenvironm Sci, Tsukuba, Ibaraki 3058604, Japan.
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Why
do you think your paper is highly cited?
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“...our report would be helpful to establish methods of acrylamide analysis in food samples.”
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Acrylamide is a compound classified in Group 2A, which means
"probably carcinogenic to humans," by the International
Agency for Research on Cancer (IARC). Thus the press release
announcing the presence of acrylamide in fried and oven-cooked foods
by the University of Stockholm and the National Food Administration
of Sweden in April 2002 caused worldwide concern for human health.
After this report, analyses of acrylamide in foods were urgently
performed in many countries. Our paper described modified methods of
LC-MS/MS and GC-MS analyses previously reported by other research
groups, which are useful for determination of acrylamide in a wide
range of processed foods. We showed that analytical values obtained
by the two methods highly correlate for various processed food
samples. This would be one of the main reasons why our paper has
been cited by food chemists involved in acrylamide analysis. Within
these two years, abundant data on acrylamide content in foods have
been reported from Western countries while the data on Asian foods
are still scarce. Our paper was published as the first report of
acrylamide in Japanese food in an international journal and cited as
representative of data on Asian foods. We think this is another
reason for the citations.
Does
it describe a new discovery or new methodology that's useful to
others?
As described above, our report would be helpful to establish
methods of acrylamide analysis in food samples. In addition, our
data of acrylamide in Japanese foods are useful for the estimation
of exposure of Asian people to acrylamide.
Could
you summarize the significance of your paper in layman's terms?
Acrylamide concentrations in processed foods purchased in
Japanese markets were analyzed by LC-MS/MS and GC-MS methods. We
confirmed that the ranges of acrylamide concentration in potato
chips, cookies, and breakfast cereals observed in this survey were
within those reported from Western countries. Rice crackers, which
are processed by grilling at 200-300° C
for several minutes or frying at
160-260° C, also for several minutes,
contained 20 to 300 m g/kg acrylamide.
Non-whole potato-based snacks, which are made from potato starch,
wheat flour, or corn whole mill flour, shaped, fried, and seasoned,
contained a similar level of acrylamide as the rice crackers.
Instant noodles and won-tons contained about 10 to 60 m
g/kg acrylamide, with the one exception being the concentration over
500 m g/kg. Roasted barley grains used
for tea substitutes or herb tea blends contained 200-600 m
g/kg acrylamide, which is comparable to the concentration in coffee
powder. Other Japanese and Asian-type foods measured in this study
contained around 100 m g/kg acrylamide or
less. These data should be useful for an estimation of the
exposure of Asian people to acrylamide, that is, for a risk
assessment of this compound.
How
did you become involved in this research?
Our institute, the National Food Research Institute, is
implementing wide-range research projects on food science and
technology as one of Japan’s main public research institutions.
The Incorporated Administrative Agency is supported mostly by the
Ministry of Agriculture, Forestry and Fisheries. The mission of the
Institute is to provide Japanese society with a healthy and enriched
life and a secure supply of safe food through conducting research.
After the press release on the presence of acrylamide in
common-processed foods by the University of Stockholm and the
National Food Administration of Sweden in April 2002, our institute
organized a cross-divisional working group for this issue and
started the analysis of acrylamide in processed foods in the
Japanese market. We are now expanding the research to examine the
effects of the storage conditions of potato tubers on acrylamide
formation in potato chips during frying.
Mitsuru Yoshida, Ph.D.
Head of Molecular Structure and Dynamics Lab
Analytical Science Division
National Food Research Institute
Tsukuba, Ibaraki, Japan
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ESI Special Topics,
July 2004
Citing URL - http://www.esi-topics.com/nhp/2004/july-04-MitsuruYoshida.html
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