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New Hot Paper Comments

By Mitsuru Yoshida

ESI Special Topics, July 2004
Citing URL - http://www.esi-topics.com/nhp/2004/july-04-MitsuruYoshida.html

Mitsuru Yoshida answers a few questions about this month's new hot paper in the field of Agricultural Sciences.


From •>>July 2004

Field: Agricultural Sciences
Article Title: Analysis of acrylamide by LC-MS/MS and GC-MS in processed Japanese foods
Authors: Ono, H;Chuda, Y;Ohnishi-Kameyama, M;Yada, H;Ishizaka, M;Kobayashi, H;Yoshida, M
Journal: FOOD ADDIT CONTAM
Volume: 20
Page: 215-220
Year: 2003
* Natl Food Res Inst, 2-1-2 Kannondai, Tsukuba, Ibaraki 3058642, Japan.
* Natl Food Res Inst, Tsukuba, Ibaraki 3058642, Japan.
* Ctr Food Qual Labeling & Consumer Serv, Kitabukuro, Saitama 3309731, Japan.
* Natl Inst Agroenvironm Sci, Tsukuba, Ibaraki 3058604, Japan.

ST:  Why do you think your paper is highly cited?


“...our report would be helpful to establish methods of acrylamide analysis in food samples.”

Acrylamide is a compound classified in Group 2A, which means "probably carcinogenic to humans," by the International Agency for Research on Cancer (IARC). Thus the press release announcing the presence of acrylamide in fried and oven-cooked foods by the University of Stockholm and the National Food Administration of Sweden in April 2002 caused worldwide concern for human health. After this report, analyses of acrylamide in foods were urgently performed in many countries. Our paper described modified methods of LC-MS/MS and GC-MS analyses previously reported by other research groups, which are useful for determination of acrylamide in a wide range of processed foods. We showed that analytical values obtained by the two methods highly correlate for various processed food samples. This would be one of the main reasons why our paper has been cited by food chemists involved in acrylamide analysis. Within these two years, abundant data on acrylamide content in foods have been reported from Western countries while the data on Asian foods are still scarce. Our paper was published as the first report of acrylamide in Japanese food in an international journal and cited as representative of data on Asian foods. We think this is another reason for the citations.

ST:  Does it describe a new discovery or new methodology that's useful to others?

As described above, our report would be helpful to establish methods of acrylamide analysis in food samples. In addition, our data of acrylamide in Japanese foods are useful for the estimation of exposure of Asian people to acrylamide.

ST:  Could you summarize the significance of your paper in layman's terms?

Acrylamide concentrations in processed foods purchased in Japanese markets were analyzed by LC-MS/MS and GC-MS methods. We confirmed that the ranges of acrylamide concentration in potato chips, cookies, and breakfast cereals observed in this survey were within those reported from Western countries. Rice crackers, which are processed by grilling at 200-300° C for several minutes or frying at 160-260° C, also for several minutes, contained 20 to 300 m g/kg acrylamide. Non-whole potato-based snacks, which are made from potato starch, wheat flour, or corn whole mill flour, shaped, fried, and seasoned, contained a similar level of acrylamide as the rice crackers. Instant noodles and won-tons contained about 10 to 60 m g/kg acrylamide, with the one exception being the concentration over 500 m g/kg. Roasted barley grains used for tea substitutes or herb tea blends contained 200-600 m g/kg acrylamide, which is comparable to the concentration in coffee powder. Other Japanese and Asian-type foods measured in this study contained around 100 m g/kg acrylamide or less. These data should be useful for an estimation of the exposure of Asian people to acrylamide, that is, for a risk assessment of this compound.

ST:  How did you become involved in this research?

Our institute, the National Food Research Institute, is implementing wide-range research projects on food science and technology as one of Japan’s main public research institutions. The Incorporated Administrative Agency is supported mostly by the Ministry of Agriculture, Forestry and Fisheries. The mission of the Institute is to provide Japanese society with a healthy and enriched life and a secure supply of safe food through conducting research. After the press release on the presence of acrylamide in common-processed foods by the University of Stockholm and the National Food Administration of Sweden in April 2002, our institute organized a cross-divisional working group for this issue and started the analysis of acrylamide in processed foods in the Japanese market. We are now expanding the research to examine the effects of the storage conditions of potato tubers on acrylamide formation in potato chips during frying.End

Mitsuru Yoshida, Ph.D.
Head of Molecular Structure and Dynamics Lab
Analytical Science Division
National Food Research Institute
Tsukuba, Ibaraki, Japan

ESI Special Topics, July 2004
Citing URL - http://www.esi-topics.com/nhp/2004/july-04-MitsuruYoshida.html

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