Beginning in mid-February 2008, the 1997-2007 online version of the Science Watch® newsletter, ESI-Topics.com, and in-cites.com, will all be featured together on the redesigned ScienceWatch.com. All previous content from the three sites will be permanently archived, and remain accessible from any existing bookmarks to the archived pages. No new content will be added to this site. Updates and new content (updated biweekly) are available at ScienceWatch.com now.

New Hot Paper Comments

By Steve Oliver

ESI Special Topics, September 2004
Citing URL - http://www.esi-topics.com/nhp/2004/september-04-SteveOliver.html

Steve Oliver answers a few questions about this month's new hot paper in the field of Multidisciplinary.


From •>>September 2004

Field: Multidisciplinary
Article Title: Functional genomic hypothesis generation and experimentation by a robot scientist
Authors: King, RD;Whelan, KE;Jones, FM;Reiser, PGK;Bryant, CH;Muggleton, SH;Kell, DB;Oliver, SG
Journal: NATURE
Volume: 427
Page: 247-252
Year: JAN 15 2004
* Univ Manchester, Sch Biol Sci, 2-205 Stopford Bldg, Manchester M13 9PT, Lancs, England.
* Univ Manchester, Sch Biol Sci, Manchester M13 9PT, Lancs, England.
* Univ Wales, Dept Comp Sci, Aberystwyth SY23 3DB, Dyfed, Wales.
* Robert Gordon Univ, Sch Comp, Aberdeen AB10 1FR, Scotland.
* Univ London Imperial Coll Sci Technol & Med, Dept Comp, London SW7 2AZ, England.
* UMIST, Dept Chem, Manchester M60 1QD, Lancs, England.

• This paper has also been named the Fast Breaking Paper in Multidisciplinary for October 2004.
•This paper has also been named the New Hot Paper in Computer Science for November 2005.

ST:  Why do you think your paper is highly cited?


“We have designed a system in which a computer designs scientific experiments, instructs a robot to carry out those experiments, and records the results.”

I think it has captured people's imaginations and led them to question what is truly creative in the scientific process. It has also raised questions as to how principal investigators really treat their students and post-docs., whether as collaborators in the scientific process or if, they instead, use them as "discovery robots."

ST:  Does it describe a new discovery or new methodology that's useful to others?

It's a new methodology that automates the process of scientific discovery, within a well-defined domain, thereby freeing researchers' time for doing genuinely creative things.

ST:  Could you summarize the significance of your paper in layman's terms?

Scientific research is a complex activity, but often the path to a scientific discovery is clear, even if the nature of that discovery is not. We have designed a system in which a computer designs scientific experiments, instructs a robot to carry out those experiments, and records the results. The computer then compares the results with its existing hypothesis, revises the hypothesis, if necessary, and designs the next round of experiments to test it.

ST:  How did you become involved in this research?

Ross King (a computer scientist at Aberystwyth) and I were trying to use machine learning methods to construct biological systems directly from experimental data. We reasoned that it should be possible to get the computer to design and execute the experiments as well. So, together with Stephen Muggleton (a computer scientist who invented inductive logic programming) and Douglas Kell (a microbiologist and analytical scientist, then at Aberystwyth) we set out to design and build a robot scientist. Click here to see robot scientist. End

Stephen G. Oliver, FMedSci
Professor of Genomics
School of Biological Sciences
University of Manchester
Manchester, UK

ESI Special Topics, September 2004
Citing URL - http://www.esi-topics.com/nhp/2004/september-04-SteveOliver.html

•> Search Special Topics
New Hot Papers Menu || All Topics Menu
New Hot Papers Comments Menu
Help || About || Contact

ScienceWatch.com - Tracking Trends and Perfomance in Basic Research
Go to the new ScienceWatch.com

Write to the Webmaster with questions/comments. Terms of Usage.
The Research Services Group of Thomson Scientific |
(c) 2008 The Thomson Corporation.