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Stem Cells (2007) Menu

ESI Special Topics, November 2007
Citing URL: http://esi-topics.com/stemcells2007/rf/rf1.html

Stem Cells (2007)

RESEARCH FRONT  MAPS  | Map methodology

Stem Cells Research Front Maps
    Map Title and Accompanying Interviews:
Map 1 »»» CULTURING HUMAN EMBRYONIC STEM CELLS
Alberto Hayek discusses his featured Research Front Map paper (locate paper in map), Beattie GM, et al., "Activin A maintains the plruipotency of human embryonic stem cells in the absence of feeder layers," Stem Cells 23(4): 489-95 April 2005.
(Added November 2007)
Outi Hovatta comments on his featured Research Front Map paper (locate paper in map), Hovatta O, et al., "A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells," Hum. Reprod. 18(7): 1404-9, July 2003. A related figure of his work is also ncluded.
(Added December 2007)
An interview with Chunhui Xu who discusses his paper (locate paper in map), Xu CH, et al., "Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium," Stem Cells 23(3): 315-23, March 2005.
(Added December 2007)
Map 2 • STEM-CELLS FOR MYOCARDIAL REGENERATION
Map 3 • REGULATION OF EMBRYONIC STEM CELLS
Map 4 • CANCER STEM CELLS

Xu-2001 Richards-2002 Amit-2003 Hovatta-2003 Amit-2004 Cowan-2004 Heins-2004 Daheron-2004 Brimble-2004 Xu-2005 Stojkovic-2005 Xu-2005 Beattie-2005 James-2005 Klimanskaya-2005 Wang-2005 Ludwig-2006 Pyle-2006 Lu-2006 Yao-2006 Xiao-2006
 CULTURING HUMAN EMBRYONIC STEM CELLS

 Core Papers 

Label: Xu-2001
 Title: Feeder-free growth of undifferentiated human embryonic stem cells
Journal: NAT BIOTECHNOL, 19 (10): 971-974 OCT 2001
Citations: 373
Authors: Xu, CH;Inokuma, MS;Denham, J;Golds, K;Kundu, P;Gold, JD;Carpenter, MK
Addresses:
Geron Corp, 230 Consitut Dr, Menlo Pk, CA 94025 USA
Geron Corp, Menlo Pk, CA 94025 USA


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Label: Richards-2002
 Title: Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells
Journal: NAT BIOTECHNOL, 20 (9): 933-936 SEP 2002
Citations: 169
Authors: Richards, M;Fong, CY;Chan, WK;Wong, PC;Bongso, A
Addresses:
Natl Univ Singapore, Dept Obstet & Gynaecol, Kent Ridge, Singapore 119260, Singapore
Natl Univ Singapore, Dept Obstet & Gynaecol, Singapore 119260, Singapore
Natl Univ Singapore, Dept Sci Biol, Singapore 119260, Singapore


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Label: Cowan-2004
 Title: Derivation of embryonic stem-cell lines from human blastocysts
Journal: N ENGL J MED, 350 (13): 1353-1356 MAR 25 2004
Citations: 165
Authors: Cowan, CA;Klimanskaya, I;McMahon, J;Atienza, J;Witmyer, J;Zucker, JP;Wang, SP;Morton, CC;McMahon, AP;Powers, D;Melton, DA
Addresses:
Harvard Univ, Howard Hughes Med Inst, Cambridge, MA 02138 USA
Harvard Univ, Howard Hughes Med Inst, Cambridge, MA 02138 USA
Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA
Boston IVF, Waltham, MA USA
Harvard Univ, Sch Med, Boston, MA USA
Brigham & Womens Hosp, Dept Obstet Gynecol & Reprod Biol, Boston, MA 02115 USA
Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA


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Label: Xu-2005
 Title: Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells
Journal: NAT METHODS, 2 (3): 185-190 MAR 2005
Citations: 146
Authors: Xu, RH;Peck, RM;Li, DS;Feng, XZ;Ludwig, T;Thomson, JA
Addresses:
WiCell Res Inst, Madison, WI 53707 USA
WiCell Res Inst, Madison, WI 53707 USA
Univ Wisconsin, Sch Med, Dept Anat, Wisconsin Natl Primate Res Ctr, Madison, WI 53706 USA
Genome Ctr Wisconsin, Madison, WI 53706 USA


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Label: Amit-2004
 Title: Feeder layer- and serum-free culture of human embryonic stem cells
Journal: BIOL REPROD, 70 (3): 837-845 MAR 2004
Citations: 131
Authors: Amit, M;Shariki, C;Margulets, V;Itskovitz-Eldor, J
Addresses:
Rambam Med Ctr, Dept Obstet & Gynecol, POB 9602, IL-31096 Haifa, Israel
Rambam Med Ctr, Dept Obstet & Gynecol, IL-31096 Haifa, Israel
Technion Israel Inst Technol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel


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Label: Amit-2003
 Title: Human feeder layers for human embryonic stem cells
Journal: BIOL REPROD, 68 (6): 2150-2156 JUN 2003
Citations: 107
Authors: Amit, M;Margulets, V;Segev, H;Shariki, K;Laevsky, I;Coleman, R;Itskovitz-Eldor, J
Addresses:
Rambam Med Ctr, Dept Obstet & Gynecol, POB 9602, IL-31096 Haifa, Israel
Rambam Med Ctr, Dept Obstet & Gynecol, IL-31096 Haifa, Israel
Technion Israel Inst Technol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel
Rambam Med Ctr, Genet Inst, IL-31096 Haifa, Israel


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Label: Hovatta-2003
 Title: A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells
Journal: HUM REPROD, 18 (7): 1404-1409 JUL 2003
Citations: 102
Authors: Hovatta, O;Mikkola, M;Gertow, K;Stromberg, AM;Inzunza, J;Hreinsson, J;Rozell, B;Blennow, E;Andang, M;Ahrlund-Richter, L
Addresses:
Huddinge Univ Hosp, Karolinska Inst, Dept Clin Sci, S-14186 Huddinge, Sweden
Huddinge Univ Hosp, Karolinska Inst, Dept Clin Sci, S-14186 Huddinge, Sweden
Huddinge Univ Hosp, Karolinska Inst, Clin Res Ctr, S-14186 Huddinge, Sweden
Karolinska Inst, Mol Neurobiol Lab, S-17177 Stockholm, Sweden
Karolinska Inst, Ctr Mol Med, S-17177 Stockholm, Sweden
Special Topics Research Front Map Interview with Outi Hovatta


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Label: James-2005
 Title: TGF beta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem
Journal: DEVELOPMENT, 132 (6): 1273-1282 MAR 2005
Citations: 72
Authors: James, D;Levine, AJ;Besser, D;Hemmati-Brivanlou, A
Addresses:
Rockefeller Univ, Lab Mol Vertebrate Embryol, 1230 York Ave, New York, NY 10021 USA
Rockefeller Univ, Lab Mol Vertebrate Embryol, New York, NY 10021 USA


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Label: Ludwig-2006
 Title: Derivation of human embryonic stem cells in defined conditions
Journal: NAT BIOTECHNOL, 24 (2): 185-187 FEB 2006
Citations: 64
Authors: Ludwig, TE;Levenstein, ME;Jones, JM;Berggren, WT;Mitchen, ER;Frane, JL;Crandall, LJ;Daigh, CA;Conard, KR;Piekarczyk, MS;Llanas, RA;Thomson, JA
Addresses:
WiCell Res Inst, POB 7365, Madison, WI 53707 USA
WiCell Res Inst, Madison, WI 53707 USA
Genome Ctr Wisconsin, Madison, WI 53706 USA
Univ Wisconsin, Wisconsin Natl Primate Res Ctr, Madison, WI 53715 USA
Univ Wisconsin, Dept Obstet & Gynecol, Sch Med, Madison, WI 53715 USA
Univ Wisconsin, Dept Anat, Sch Med, Madison, WI 53715 USA


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Label: Xu-2005
 Title: Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium
Journal: STEM CELLS, 23 (3): 315-323 MAR 2005
Citations: 63
Authors: Xu, CH;Rosler, E;Jiang, JJ;Lebkowski, JS;Gold, JD;O'Sullivan, C;Delavan-Boorsma, K;Mok, M;Bronstein, A;Carpenter, MK
Addresses:
Geron Corp, 230 Constitut Dr, Menlo Pk, CA 94025 USA
Geron Corp, Menlo Pk, CA 94025 USA
Special Topics Research Front Map Interview with Chunhui Xu


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Label: Daheron-2004
 Title: LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells
Journal: STEM CELLS, 22 (5): 770-778 2004
Citations: 62
Authors: Daheron, L;Opitz, SL;Zaehres, H;Lensch, WM;Andrews, PW;Itskovitz-Eldor, J;Daley, GQ
Addresses:
Harvard Univ, Sch Med, Div Pediat Hematol Oncol, Dept Biol Chem & Mol Pharmacol,Childrens Hosp, 300 Longwood Ave, Boston, MA 02115 USA
Harvard Univ, Sch Med, Div Pediat Hematol Oncol, Dept Biol Chem & Mol Pharmacol,Childrens Hosp, Boston, MA 02115 USA
Whitehead Inst Biomed Res, Cambridge, MA 02142 USA
Dana Farber Canc Inst, Boston, MA 02115 USA
Univ Sheffield, Dept Biomed Sci, Sheffield S10 2TN, S Yorkshire, England
Technion Univ, Rambam Med Ctr, Haifa, Israel


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Label: Beattie-2005
 Title: Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers
Journal: STEM CELLS, 23 (4): 489-495 APR 2005
Citations: 59
Authors: Beattie, GM;Lopez, AD;Bucay, N;Hinton, A;Firpo, MT;King, CC;Hayek, A
Addresses:
Whittier Inst, 9894 Genesse Ave, La Jolla, CA 92037 USA
Univ Calif San Diego, Dept Pediat, Whittier Inst, San Diego, CA 92103 USA
Univ Calif San Francisco, Dept Obstet Gynecol & Reprod Sci, San Francisco, CA 94143 USA
Special Topics Research Front Map Interview with Alberto Hayek


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Label: Klimanskaya-2005
 Title: Human embryonic stem cells derived without feeder cells
Journal: LANCET, 365 (9471): 1636-1641 MAY 7 2005
Citations: 59
Authors: Klimanskaya, I;Chung, Y;Meisner, L;Johnson, J;West, MD;Lanza, R
Addresses:
Adv Cell Technol, 381 Plantat St, Worcester, MA 01605 USA
Adv Cell Technol, Worcester, MA 01605 USA
Univ Wisconsin, Sch Med, Dept Pathol & Lab Med, Madison, WI USA
Wisconsin State Lab Hyg, Cytogenet Lab, Madison, WI USA
Wake Forest Univ, Bowman Gray Sch Med, Inst Regenerat Med, Winston Salem, NC USA


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Label: Heins-2004
 Title: Derivation, characterization, and differentiation of human embryonic stem cells
Journal: STEM CELLS, 22 (3): 367-376 2004
Citations: 58
Authors: Heins, N;Englund, MCO;Sjoblom, C;Dahl, U;Tonning, A;Bergh, C;Lindahl, A;Hanson, C;Semb, H
Addresses:
Lund Univ, Endocrinol Sect, Klin Gatan 26,BMC,B10, SE-22184 Lund, Sweden
Sahlgrens Univ Hosp, Dept Clin Chem & Transfus Med, Inst Lab Med, S-41345 Gothenburg, Sweden
Sahlgrens Univ Hosp, Dept Obstet & Gynaecol, S-41345 Gothenburg, Sweden
Univ Gothenburg, Dept Biochem Med, Gothenburg, Sweden
Cellartis AB, Gothenburg, Sweden


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Label: Stojkovic-2005
 Title: An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells
Journal: STEM CELLS, 23 (3): 306-314 MAR 2005
Citations: 43
Authors: Stojkovic, P;Lako, M;Stewart, R;Przyborski, S;Armstrong, L;Evans, J;Murdoch, A;Strachan, T;Stojkovic, M
Addresses:
Univ Newcastle, Ctr Stem Cell Biol & Dev Genet, Cent Pkwy, Newcastle Upon Tyne NE1 3BZ, Tyne & Wear, England
Univ Newcastle, Ctr Stem Cell Biol & Dev Genet, Newcastle Upon Tyne NE1 3BZ, Tyne & Wear, England
Univ Durham, Sch Biol & Biomed Sci, Durham, England
Newcastle Fertil Ctr Life, Newcastle Fertil Ctr Life, Newcastle Upon Tyne, Tyne & Wear, England


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Label: Brimble-2004
 Title: Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001
Journal: STEM CELLS DEV, 13 (6): 585-597 DEC 2004
Citations: 40
Authors: Brimble, SN;Zeng, XM;Weiler, DA;Luo, YQ;Liu, Y;Lyons, IG;Freed, WJ;Robins, AJ;Rao, MS;Schulz, TC
Addresses:
BresaGen Inc, 111 Riverbend Rd, Athens, GA 30605 USA
BresaGen Inc, Athens, GA 30605 USA
NIDA, Cellular Neurobiol Branch, Dept Hlth & Human Serv, Baltimore, MD 21224 USA
NIA, Neurosci Lab, Dept Hlth & Human Serv, Baltimore, MD 21224 USA


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Label: Wang-2005
 Title: Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development
Journal: BLOOD, 105 (12): 4598-4603 JUN 15 2005
Citations: 37
Authors: Wang, LS;Li, L;Menendez, P;Cerdan, C;Bhatia, M
Addresses:
Univ Western Ontario, Robarts Res Inst, Krembil Ctr Stem Cell Biol & Regenerat Med, 100 Perth Dr, London, ON N6A 5K8, Canada
Univ Western Ontario, Robarts Res Inst, Krembil Ctr Stem Cell Biol & Regenerat Med, London, ON N6A 5K8, Canada
Univ Western Ontario, Dept Microbiol & Immunol, London, ON N6A 5K8, Canada


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Label: Pyle-2006
 Title: Neurotrophins mediate human embryonic stem cell survival
Journal: NAT BIOTECHNOL, 24 (3): 344-350 MAR 2006
Citations: 22
Authors: Pyle, AD;Lock, LF;Donovan, PJ
Addresses:
Univ Calif Irvine, Stem Cell Program, Hewitt Hall, Irvine, CA 92697 USA
Univ Calif Irvine, Stem Cell Program, Irvine, CA 92697 USA
Univ Calif Irvine, Dept Dev & Cell Biol, Irvine, CA 92697 USA
Univ Calif Irvine, Dept Biol Chem, Irvine, CA 92697 USA
Johns Hopkins Univ, Sch Med, Germ Cell & Stem Cell Grp, Baltimore, MD 21205 USA
Johns Hopkins Univ, Sch Med, Genet Models Grp, Stem Cell Biol Program,Inst Cell Engn, Baltimore, MD 21205 USA


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Label: Yao-2006
 Title: Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions
Journal: PROC NAT ACAD SCI USA, 103 (18): 6907-6912 MAY 2 2006
Citations: 19
Authors: Yao, S;Chen, S;Clark, J;Hao, E;Beattie, GM;Hayek, A;Ding, S
Addresses:
Scripps Res Inst, Dept Chem, SR202, La Jolla, CA 92037 USA
Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
Univ Calif San Diego, Dept Pediat, Whittier Inst, La Jolla, CA 92093 USA


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Label: Xiao-2006
 Title: Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
Journal: STEM CELLS, 24 (6): 1476-1486 JUN 2006
Citations: 14
Authors: Xiao, L;Yuan, X;Sharkis, SJ
Addresses:
Johns Hopkins Univ, Sch Med, Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Room 551,1550 Orleans St, Baltimore, MD 21231 USA
Johns Hopkins Univ, Sch Med, Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Baltimore, MD 21231 USA


[Back to Map]     

Label: Lu-2006
 Title: Defined culture conditions of human embryonic stem cells
Journal: PROC NAT ACAD SCI USA, 103 (15): 5688-5693 APR 11 2006
Citations: 12
Authors: Lu, J;Hou, RH;Booth, CJ;Yang, SH;Snyder, M
Addresses:
Yale Univ, Dept Mol Cellular & Dev Biol, POB 208103, New Haven, CT 06520 USA
Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA
Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA
Hosp St Raphael, Dept Med, New Haven, CT 06511 USA
Yale Univ, Sch Med, Dept Neurol, New Haven, CT 06510 USA
Yale Univ, Sch Med, Comparat Med Sect, New Haven, CT 06510 USA
Natl Taiwan Univ Hosp, Dept Surg, Div Neurosurg, Taipei 100, Taiwan


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This special topic was originally featured in November 2001 and was called Embryonic Stem Cells. To view the archived Embryonic Stem Cells topic, click here.

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ESI Special Topics, November 2007
Citing URL: http://esi-topics.com/stemcells2007/rf/rf1.html

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